Kuma Kuma Kuma Bear
Cute girls doing cute things the isekai? When self proclaimed hermit Yuna opens a special event box in her VRMMORPG she ends up transported to a fantasy world with her event reward (a set of bear themed equipment) and a ton of money. The main hook of her equipment being the source of abilities meaning she can never get rid of it is still a source of amusement for me even after 5 volumes, the joke hasn't gotten old yet.
The various arcs are more or less what one might expect from a fantasy world isekai, adventurer and merchant guilds, nobles, fighting monsters, food, etc. the fact that the protagonist is a girl in a bear onesie gives it all a fresh coat of paint and helps keep the tone fairly light hearted.